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HOW TO USE In this web server, full sequence and binding site classifications are stored and a web interface enabling users to find the related information for a query receptor. Using as input the uniprot protein code or the fasta sequence of a GPCR, the web application displays detailed information about it and produces several tables and analysis graphs. The information is intended to be displayed on a highly user-friendly interface.
Once the input is introduced, the server generates four different sections: i) TM sequence classification: It shows the closest resembling branch of protein according to our pre-calculated phylogenetic tree. This is very useful to observe the closest similar proteins to users’ input. The phylogenetic tree is browsable, adjusting the number of branches the user wants to see. Users can zoom in and out of tree branches, adjusting the number of nodes they want to observe. Branches of receptors with known crystal structure are shown in orange.
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