Publications
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2011
- Sansuk, K. Deupi, X. Torrecillas, IR. Jongejan, A. Nijmeijer, S. Bakker, RA. Pardo, L. Leurs, R.
“A Structural Insight into the Reorientation of Transmembrane Domains 3 and 5 during Family A G Protein-Coupled Receptor Activation.”
Mol Pharmacol 79(2) 262–9
- Orcajo-Rincon, AL. Ortega-Gutierrez, S. Serrano, P. Torrecillas, IR. Wuthrich, K. Campillo, M. Pardo, L. Viso, A. Benhamu, B. Lopez-Rodriguez, ML.
“Development of Non-Peptide Ligands of Growth Factor Receptor-Bound Protein 2-Src Homology 2 Domain Using Molecular Modeling and NMR Spectroscopy.”
J Med Chem 54(4) 1096–1100 - Bosch-Presegue, L. Iarriccio, L. Aguila, M. Toledo, D. Ramon, E. Cordomi, A. Garriga, P.
“Hydrophobic amino acids at the cytoplasmic ends of helices 3 and 6 of rhodopsin conjointly modulate transducin activation.”
Arch Biochem Biophys 506(2) 142–9 - Gonzalez, A. Murcia, M. Benhamu, B. Campillo, M. Lopez-Rodriguez, ML. Pardo, L.
“The importance of solvation in the design of ligands targeting membrane proteins”
Med Chem Commun 2(3) 160–164 - Sriphrapradang, C. Tenenbaum-Rakover, Y. Weiss, M. Barkoff, MS. Admoni, O. Kawthar, D. Caltabiano, G. Pardo, L. Dumitrescu, AM. Refetoff, S.
“The coexistence of a novel inactivating mutant thyrotropin receptor allele with two thyroid peroxidase mutations: a genotype-phenotype correlation.”
J Clin Endocrinol Metab 96(6) e1001–e1006 - Bosch-Presegue, L. Ramon, E. Toledo, D. Cordomi, A. Garriga, P.
“Alterations in the photoactivation pathway of rhodopsin mutants associated with retinitis pigmentosa.”
FEBS J 278(9) 1493–1505 - Perez-Victoria, JM. Bavchvarov, BI. Torrecillas, IR. Martinez-Garcia, M. Lopez-Martin, C. Campillo, M. Castanys, S. Gamarro, F.
“Sitamaquine overcomes ABC-mediated resistance to miltefosine and antimony in Leishmania.”
Antimicrob Agents Chemother 55(8) 3838–44 - Solans-Laque, R. Lopez-Hernandez, A. Angel, Bosch-Gil, J. Palacios, A. Campillo, M. Vilardell-Tarres, M.
“Risk, Predictors, and Clinical Characteristics of Lymphoma Development in Primary Sjogren\’s Syndrome.”
Semin Arthritis Rheum 41(3) 415–23 - Gonzalez, A. Perez-Acle, T. Pardo, L. Deupi, X.
“Molecular Basis of Ligand Dissociation in beta-Adrenergic Receptors.”
PLoS One 6(9) e23815– - Christiansen, E. Urban, C. Grundmann, M. Due-Hansen, ME. Hagesaether, E. Schmidt, J. Pardo, L. Ullrich, S. Kostenis, E. Kassack, M. Ulven, T.
“Identification of a Potent and Selective Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist with Favorable Physicochemical and in Vitro ADME Properties.”
J Med Chem 54(19) 6691–703 - Toledo, D. Ramon, E. Aguila, M. Cordomi, A. Perez, JJ. Mendes, HF. Cheetham, ME. Garriga, P.
“Molecular mechanisms of disease for mutations at gly-90 in rhodopsin.”
J Biol Chem 286(46) 39993–40001 - Marco, I. Valhondo, M. Martin-Fontecha, M. Vazquez-Villa, H. Del, Rio, J. Planas, A. Sagredo, O. Ramos, JA. Torrecillas, IR. Pardo, L. Frechilla, D. Benhamu, B. Lopez-Rodriguez, ML.
“New Serotonin 5-HT(1A) Receptor Agonists with Neuroprotective Effect against Ischemic Cell Damage.”
J Med Chem 54(23) 7986–7999