Publications

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2011


  1. Sansuk, K. Deupi, X. Torrecillas, IR. Jongejan, A. Nijmeijer, S. Bakker, RA. Pardo, L. Leurs, R.
    “A Structural Insight into the Reorientation of Transmembrane Domains 3 and 5 during Family A G Protein-Coupled Receptor Activation.”
    Mol Pharmacol 79(2) 262–9
    Abstract PDF PubMed Link

  2. Orcajo-Rincon, AL. Ortega-Gutierrez, S. Serrano, P. Torrecillas, IR. Wuthrich, K. Campillo, M. Pardo, L. Viso, A. Benhamu, B. Lopez-Rodriguez, ML.
    “Development of Non-Peptide Ligands of Growth Factor Receptor-Bound Protein 2-Src Homology 2 Domain Using Molecular Modeling and NMR Spectroscopy.”
    J Med Chem 54(4) 1096–1100
    Abstract PDF PubMed Link

  3. Bosch-Presegue, L. Iarriccio, L. Aguila, M. Toledo, D. Ramon, E. Cordomi, A. Garriga, P.
    “Hydrophobic amino acids at the cytoplasmic ends of helices 3 and 6 of rhodopsin conjointly modulate transducin activation.”
    Arch Biochem Biophys 506(2) 142–9
    Abstract PDF PubMed Link

  4. Gonzalez, A. Murcia, M. Benhamu, B. Campillo, M. Lopez-Rodriguez, ML. Pardo, L.
    “The importance of solvation in the design of ligands targeting membrane proteins”
    Med Chem Commun 2(3) 160–164
    Abstract PDF

  5. Sriphrapradang, C. Tenenbaum-Rakover, Y. Weiss, M. Barkoff, MS. Admoni, O. Kawthar, D. Caltabiano, G. Pardo, L. Dumitrescu, AM. Refetoff, S.
    “The coexistence of a novel inactivating mutant thyrotropin receptor allele with two thyroid peroxidase mutations: a genotype-phenotype correlation.”
    J Clin Endocrinol Metab 96(6) e1001–e1006
    Abstract PubMed Link

  6. Bosch-Presegue, L. Ramon, E. Toledo, D. Cordomi, A. Garriga, P.
    “Alterations in the photoactivation pathway of rhodopsin mutants associated with retinitis pigmentosa.”
    FEBS J 278(9) 1493–1505
    Abstract PDF PubMed Link

  7. Perez-Victoria, JM. Bavchvarov, BI. Torrecillas, IR. Martinez-Garcia, M. Lopez-Martin, C. Campillo, M. Castanys, S. Gamarro, F.
    “Sitamaquine overcomes ABC-mediated resistance to miltefosine and antimony in Leishmania.”
    Antimicrob Agents Chemother 55(8) 3838–44
    Abstract PDF PubMed Link

  8. Solans-Laque, R. Lopez-Hernandez, A. Angel, Bosch-Gil, J. Palacios, A. Campillo, M. Vilardell-Tarres, M.
    “Risk, Predictors, and Clinical Characteristics of Lymphoma Development in Primary Sjogren\’s Syndrome.”
    Semin Arthritis Rheum 41(3) 415–23
    Abstract PDF PubMed Link

  9. Gonzalez, A. Perez-Acle, T. Pardo, L. Deupi, X.
    “Molecular Basis of Ligand Dissociation in beta-Adrenergic Receptors.”
    PLoS One 6(9) e23815–
    Abstract PDF PubMed Link

  10. Christiansen, E. Urban, C. Grundmann, M. Due-Hansen, ME. Hagesaether, E. Schmidt, J. Pardo, L. Ullrich, S. Kostenis, E. Kassack, M. Ulven, T.
    “Identification of a Potent and Selective Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist with Favorable Physicochemical and in Vitro ADME Properties.”
    J Med Chem 54(19) 6691–703
    Abstract PDF PubMed Link

  11. Toledo, D. Ramon, E. Aguila, M. Cordomi, A. Perez, JJ. Mendes, HF. Cheetham, ME. Garriga, P.
    “Molecular mechanisms of disease for mutations at gly-90 in rhodopsin.”
    J Biol Chem 286(46) 39993–40001
    Abstract PDF PubMed Link

  12. Marco, I. Valhondo, M. Martin-Fontecha, M. Vazquez-Villa, H. Del, Rio, J. Planas, A. Sagredo, O. Ramos, JA. Torrecillas, IR. Pardo, L. Frechilla, D. Benhamu, B. Lopez-Rodriguez, ML.
    “New Serotonin 5-HT(1A) Receptor Agonists with Neuroprotective Effect against Ischemic Cell Damage.”
    J Med Chem 54(23) 7986–7999
    Abstract PDF PubMed Link